Item #4 of 10

Corticotropin-releasing factor _________________.

is synthesized in the hypothalamus;
is a substance that has not yet been experimentally isolated and verified;
stimulates the release of adrenocorticotrophic hormone (ACTH) from the anterior pituitary;
stimulates the synthetic activity of the anterior pituitary;
all of the alternatives provided are correct;

CORRECT - Yes, corticotropin-releasing factor has not yet been isolated, but is thought to be produced by the hypothalamus. When secreted by the hypothalamus, this releasing factor stimulates the synthesis of ACTH by the anterior pituitary.

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